About PRP

What is Platelet Rich Plasma (PRP) Therapy?

The use of platelet rich plasma (PRP) has spanned multiple fields of medicine including orthopedics, pain relief, wound healing and most recently dermatology (aesthetics/hair loss). Platelets are blood products found in the bone marrow. Platelets contain more than 30 bioactive proteins – many of which have important roles in tissue healing and stem cell activation. Seven primary protein growth factors are secreted by platelets and are critical in the tissue healing process. These growth factors include:

  • Platelet derived growth factor(a-b)
  • Transforming growth factor(TGF alpha-beta)
  • Vascular endothelial growth factor(VEGF)
  • Epidermal growth factor(EGF)
  • Fibroblast growth factor(FGF)
  • Connective tissue growth factor(CTGF)
  • Insulin like growth factor-1(IGF-1)

Platelets activate these growth factors which then bind to stem cells, osteoblasts, fibroblasts, endothelial cells and epidermal cells. These activated growth factors support stem cell migration, promote blood vessel growth, and stimulate protein and collagen synthesis, promote neovascularization, enhance healing and motivate new cell growth.